| 1 | Thiago Silva | Associazione Calcio Milan | Paris Saint-Germain Football Club | €42M | 14 July 2012 |
| 2 | Lucas Moura | São Paulo | Paris Saint-Germain Football Club | €40M | 1 January 2013 |
| 3 | Axel Witsel | Benfica | Zenit | €40M | 3 September 2012 |
| 4 | Hulk | Futebol Clube do Porto | Zenit | €40M | 3 September 2012 |
| 5 | Luka Modrić | Tottenham Hotspur Football Club | Real Madrid Club de Fútbol | €35M | 27 August 2012 |
| 6 | Mario Balotelli | Manchester City Football Club | Associazione Calcio Milan | €20M | 31 January 2013 |
| 7 | Joe Allen | Swansea City | Liverpool Football Club | €19M | 10 August 2012 |
| 8 | Santi Cazorla | Malaga | Arsenal Football Club | €19M | 7 August 2012 |
| 9 | Marco Reus | Borussia Mönchengladbach | Borussia Dortmund | €17.1M | 1 July 2012 |
| 10 | Shinji Kagawa | Borussia Dortmund | Manchester United Football Club | €16M | 1 July 2012 |
| 11 | Taison | Metalist Kharkiv (- 2016) | FC Shakhtar Donetsk | €15.2M | 11 January 2013 |
| 12 | Matija Nastasić | Associazione Calcio Fiorentina | Manchester City Football Club | €15.2M | 31 August 2012 |
| 13 | Lukas Podolski | 1. FC Köln | Arsenal Football Club | €15M | 1 July 2012 |
| 14 | Philippe Coutinho | Inter | Liverpool Football Club | €13M | 30 January 2013 |
| 15 | Lucas Ocampos | Club Atlético River Plate | Association sportive de Monaco Football Club | €13M | 16 August 2012 |
| 16 | Hugo Lloris | Olympique Lyonnais | Tottenham Hotspur Football Club | €12.6M | 31 August 2012 |
| 17 | Jan Vertonghen | Ajax | Tottenham Hotspur Football Club | €12.5M | 12 July 2012 |
| 18 | Luuk de Jong | Football Club Twente | Borussia Mönchengladbach | €12M | 18 July 2012 |
| 19 | Olivier Giroud | Montpellier HSC | Arsenal Football Club | €12M | 1 July 2012 |
| 20 | Paulo Dybala | Instituto Atlético Central Córdoba | Palermo FC | €11.9M | 20 July 2012 |
| 21 | Xherdan Shaqiri | FC Basel 1893 AG | FC Bayern München | €11.8M | 1 July 2012 |
| 22 | Wilfried Zaha | Crystal Palace Football Club | Manchester United Football Club | €11.8M | 25 January 2013 |
| 23 | Victor Moses | WIG | Chelsea Football Club | €11.5M | 24 August 2012 |
| 24 | Mateo Kovacic | Dinamo Zagreb | Inter | €11M | 31 January 2013 |
| 25 | Eduardo Salvio | Club Atlético de Madrid S.A.D. | Benfica | €11M | 31 July 2012 |
| 26 | Mário Fernandes | Grêmio | CSKA Moscow | €10.5M | 1 July 2012 |
| 27 | Gylfi Sigurdsson | 1899 Hoffenheim | Tottenham Hotspur Football Club | €10M | 4 July 2012 |
| 28 | Ganso | Santos | São Paulo | €9M | 21 September 2012 |
| 29 | Salomón Rondón | Malaga | Rubin | €9M | 5 August 2012 |
| 30 | César Azpilicueta | Olympique de Marseille | Chelsea Football Club | €8.8M | 24 August 2012 |
| 31 | Jay Rodríguez | Burnley Football Club | Southampton FC | €8.7M | 1 July 2012 |
| 32 | Nordin Amrabat | Kayserispor Kulübü | Galatasaray | €8.6M | 21 July 2012 |
| 33 | Granit Xhaka | FC Basel 1893 AG | Borussia Mönchengladbach | €8.5M | 1 July 2012 |
| 34 | Ivan Perišić | Borussia Dortmund | VfL Wolfsburg | €8M | 6 January 2013 |
| 35 | Marco Ruben | Villarreal Club de Fútbol S.A.D. | Dynamo Kyiv | €8M | 13 July 2012 |
| 36 | Davide Faraoni | Inter | Udinese Calcio | €8M | 9 July 2012 |
| 37 | Sergio Canales | Real Madrid Club de Fútbol | Valencia Club de Fútbol S. A. D. | €7.5M | 19 July 2012 |
| 38 | Sung-yueng Ki | The Celtic Football Club | Swansea City | €7M | 24 August 2012 |
| 39 | Mattia Destro | Siena FC | Genoa Cricket and Football Club | €7M | 19 July 2012 |
| 40 | Bas Dost | Sportclub Heerenveen | VfL Wolfsburg | €7M | 1 July 2012 |
| 41 | Luís Neto | Siena FC | Zenit | €6.5M | 1 February 2013 |
| 42 | Joselu | — | 1899 Hoffenheim | €6M | 8 August 2012 |
| 43 | Gökhan Töre | Hamburger Sport Verein | Rubin | €6M | 26 July 2012 |
| 44 | Ángelo Henríquez | — | Manchester United Football Club | €5.5M | 15 August 2012 |
| 45 | Dušan Tadić | Football Club Groningen | Football Club Twente | €5.5M | 1 July 2012 |
| 46 | Marko Livaja | Inter | Atalanta Bergamasca Calcio S.p.a. | €5.1M | 31 January 2013 |
| 47 | Domagoj Vida | Dinamo Zagreb | Dynamo Kyiv | €5M | 2 January 2013 |
| 48 | Youssef El Arabi | Al-Hilal Saudi FC | Granada CF | €5M | 18 July 2012 |
| 49 | Daniel Carvajal | — | Bayer Leverkusen | €5M | 11 July 2012 |
| 50 | Iván Marcano | Villarreal Club de Fútbol S.A.D. | Rubin | €5M | 1 July 2012 |