| 1 | Alexander Isak | Newcastle United Football Club | Liverpool Football Club | €145M | 1 September 2025 |
| 2 | Florian Wirtz | Bayer Leverkusen | Liverpool Football Club | €125M | 1 July 2025 |
| 3 | Hugo Ekitiké | Eintracht Frankfurt Fußball AG | Liverpool Football Club | €95M | 23 July 2025 |
| 4 | Benjamin Sesko | RB Leipzig | Manchester United Football Club | €76.5M | 9 August 2025 |
| 5 | Nick Woltemade | VfB Stuttgart | Newcastle United Football Club | €75M | 30 August 2025 |
| 6 | Victor Osimhen | Società Sportiva Calcio Napoli | Galatasaray | €75M | 31 July 2025 |
| 7 | Bryan Mbeumo | Brentford Football Club | Manchester United Football Club | €75M | 21 July 2025 |
| 8 | Antoine Semenyo | Association Football Club Bournemouth | Manchester City Football Club | €72M | 9 January 2026 |
| 9 | Martín Zubimendi | Real Sociedad de Fútbol S.A.D. | Arsenal Football Club | €70M | 6 July 2025 |
| 10 | Eberechi Eze | Crystal Palace Football Club | Arsenal Football Club | €69.3M | 23 August 2025 |
| 11 | Viktor Gyökeres | Sporting CP | Arsenal Football Club | €66.9M | 26 July 2025 |
| 12 | Xavi Simons | RB Leipzig | Tottenham Hotspur Football Club | €65M | 29 August 2025 |
| 13 | Mohammed Kudus | West Ham United Football Club | Tottenham Hotspur Football Club | €63.8M | 10 July 2025 |
| 14 | Ilya Zabarnyi | Association Football Club Bournemouth | Paris Saint-Germain Football Club | €63M | 12 August 2025 |
| 15 | Dean Huijsen | Association Football Club Bournemouth | Real Madrid Club de Fútbol | €62.5M | 1 June 2025 |
| 16 | Mateo Retegui | Atalanta Bergamasca Calcio S.p.a. | Al-Qadsiah Saudi Football Club | €61.8M | 21 July 2025 |
| 17 | Anthony Elanga | Nottingham Forest Football Club | Newcastle United Football Club | €61.4M | 11 July 2025 |
| 18 | Yoane Wissa | Brentford Football Club | Newcastle United Football Club | €57.7M | 1 September 2025 |
| 19 | Noni Madueke | Chelsea Football Club | Arsenal Football Club | €56M | 18 July 2025 |
| 20 | Jamie Gittens | Borussia Dortmund | Chelsea Football Club | €56M | 5 July 2025 |
| 21 | Tijjani Reijnders | Associazione Calcio Milan | Manchester City Football Club | €54.9M | 10 June 2025 |
| 22 | Darwin Núñez | Liverpool Football Club | Al-Hilal Saudi FC | €53M | 9 August 2025 |
| 23 | Álvaro Carreras | Benfica | Real Madrid Club de Fútbol | €50M | 14 July 2025 |
| 24 | Jørgen Strand Larsen | Wolverhampton Wanderers Football Club | Crystal Palace Football Club | €49.7M | 2 February 2026 |
| 25 | Milos Kerkez | Association Football Club Bournemouth | Liverpool Football Club | €46.9M | 1 July 2025 |
| 26 | Alejandro Garnacho | Manchester United Football Club | Chelsea Football Club | €46.2M | 30 August 2025 |
| 27 | Jacob Ramsey | Aston Villa Football Club | Newcastle United Football Club | €45.2M | 17 August 2025 |
| 28 | Franco Mastantuono | Club Atlético River Plate | Real Madrid Club de Fútbol | €45M | 14 August 2025 |
| 29 | Estêvão | Palmeiras | Chelsea Football Club | €45M | 14 July 2025 |
| 30 | Jorrel Hato | Ajax | Chelsea Football Club | €44.2M | 3 August 2025 |
| 31 | Mateus Fernandes | Southampton FC | West Ham United Football Club | €44M | 29 August 2025 |
| 32 | Omari Hutchinson | Ipswich Town | Nottingham Forest Football Club | €43.4M | 16 August 2025 |
| 33 | Dango Ouattara | Association Football Club Bournemouth | Brentford Football Club | €42.8M | 16 August 2025 |
| 34 | Lucas Paquetá | West Ham United Football Club | Flamengo | €42M | 28 January 2026 |
| 35 | Dan Ndoye | Bologna Football Club 1909 | Nottingham Forest Football Club | €42M | 31 July 2025 |
| 36 | Álex Baena | Villarreal Club de Fútbol S.A.D. | Club Atlético de Madrid S.A.D. | €42M | 2 July 2025 |
| 37 | Tyler Dibling | Southampton FC | Everton Football Club | €40.5M | 25 August 2025 |
| 38 | Conor Gallagher | Club Atlético de Madrid S.A.D. | Tottenham Hotspur Football Club | €40M | 14 January 2026 |
| 39 | Brennan Johnson | Tottenham Hotspur Football Club | Crystal Palace Football Club | €40M | 2 January 2026 |
| 40 | Kevin | FC Shakhtar Donetsk | Fulham Football Club | €40M | 1 September 2025 |
| 41 | Lucas Chevalier | Lille Olympique Sporting Club | Paris Saint-Germain Football Club | €40M | 9 August 2025 |
| 42 | Jeremie Frimpong | Bayer Leverkusen | Liverpool Football Club | €40M | 1 July 2025 |
| 43 | Jean-Clair Todibo | Olympique Gymnaste Club Nice Côte d'Azur | West Ham United Football Club | €40M | 1 July 2025 |
| 44 | Christopher Nkunku | Chelsea Football Club | Associazione Calcio Milan | €37M | 30 August 2025 |
| 45 | Rayan Aït-Nouri | Wolverhampton Wanderers Football Club | Manchester City Football Club | €36.8M | 9 June 2025 |
| 46 | Rayan Cherki | Olympique Lyonnais | Manchester City Football Club | €36.5M | 10 June 2025 |
| 47 | Ardon Jashari | Club Brugge Koninklijke Voetbalvereniging | Associazione Calcio Milan | €36M | 6 August 2025 |
| 48 | Liam Delap | Ipswich Town | Chelsea Football Club | €35.5M | 4 June 2025 |
| 49 | Ademola Lookman | Atalanta Bergamasca Calcio S.p.a. | Club Atlético de Madrid S.A.D. | €35M | 2 February 2026 |
| 50 | Dilane Bakwa | Racing Club de Strasbourg Alsace | Nottingham Forest Football Club | €35M | 1 September 2025 |